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Tuesday 07 September 2010
Method for producing bacterial biofilm on plastic support and use thereof for the screening of therapies for pneumoccocal infections print
Persona da contattare
Andrea Frosini

Tel. 0577 232361
Num. verde 800653163
Fax. 0577 232188
e-mail: frosini5@unisi.it

Settore di attivitą
Biologia molecolare
Titolo
Method for producing bacterial biofilm on plastic support and use thereof for the screening of therapies for pneumoccocal infections
Abstract
Streptococcus pneumoniae and Neisseria meningitidis both form biofilm on polystyrene microtiter plates. Gene expression profiling showed that pneumococci in lung and brain show identical patterns of gene expression as in the biofilm on plastic. This proposes the biofilm situation in microtiter plates as model system for the assay of agents of therapeutic use in meningeal or pulmonary infections
Status
Provisional USA
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